Researchers at Trinity College Dublin have found a way to breach a natural barrier at the back of the eye, in a development that could ultimately help deliver sight-improving drugs for humans.
The inner blood-retina barrier currently blocks the vast majority of clinically validated drugs for treating degenerative eye disease. But the Trinity team has demonstrated a technique in pre-clinical models to open the barrier transiently to small molecules, such as therapeutic drugs, while keeping harmful substances out.
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